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Yes, Ozempic is a once-weekly subcutaneous injection
Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4
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And there is no randomised trial that says I should be doing this
It includes visceral hypersensitivity, gut motility, immunomodulat...
