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In addition to a regulatory role in intrarenal RAS homeostasis, megalin seems also to indirectly contribute to atherosclerosis development increasing renal ANG II levels (40)

[DOI] [PubMed] [Google Scholar] 8.Piva S.R., Susko A.M., Khoja S.S., Josbeno D.A., Fitzgerald G.K., Toledo F.G.S

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The evidence has highlighted the renoprotective effects of GLP-1RAs, such as Liraglutide, Dulaglutide, and Semaglutide, in patients with type 2 DM at risk for CVD, particularly in terms of reducing albuminuria and improving glycemic control [96,97]

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