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Mechanism of Action Incretins hormones like GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are released throughout the day, increasing at mealtimes

Tirzepatide's dual-agonist mechanism provides superior glycemic control with HbA1c reductions of 1.5-2.4%, compared to 1.2-1.8% for single-agonist alternatives

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5 Microdosing GLP-1 RAs Anecdotal discussions between holistic practitioners suggest microdosing semaglutide may help people lose weight while limiting side effects
