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When this system is not coordinating well, pressure is not managed efficiently and may be pushed outward instead of contained

This, in turn, increases the numbers of L-cells, other intestinal secretory lineages, and GLP-1 secretion in both intestinal organoids and mice fed with normal chow and high-fat diet

GLP-1s represent a powerful tool to improve health outcomes, but they are not a guaranteed solution

Those populations with higher baseline liver fat or obesity experienced the greatest absolute changes

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