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Stress triggers a spike in cortisol, sparking a chain reaction that heightens fight-or-flight mode

Like you alluded to, people sometimes think that going on a GLP-1 is the lazy way to lose weight

J Appl Physiol 104(4):944951

For the same reason as above, no quantitative comparison for safety outcomes was performed
In addition, GLP-1mediated activation of PKA upregulates CREB, increasing the expression of IRS2, a cell survival factor, leading to activation of PI3K/PKB and the anti-apoptotic protein Bcl-2 (Wilson et al., 1996

My only complaint is that it is so long