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Understanding how these medications work inside the full weight ecosystem is an essential part of responsible, trauma-informed care

However, most patients adapt within 6-12 months as their intestines adjust to continuous bile exposure

Long-term ISTs are continued, and the potential for weaning to the minimum number of therapies is considered

They provide clear, practice-oriented summaries of the recommendations for each phenotype, enabling rapid translation of the evidence into clinical decision-making

The drug was also approved for reducing major adverse cardiovascular events (MACE) in T2D patients [5, 6]
