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Although there is no direct evidence at present to indicate whether metformin has anti-manic properties, these studies demonstrate that activation of the AMPK branch of the CaMKK2 signalling pathway can ameliorate depressive behaviours

236 (1), R29R42

Ryan et al., 2017

This trial was not randomized

Be cautious with anything marketed as a hormone balancing weight loss supplement, since those can interact with medications and rarely address the root problem

GLP-1s for Psoriatic Arthritis (PsA) Asthma One study of more than 3,000 adults who were overweight or had obesity found that those taking a GLP-1 had a 12 to 15 percent lower risk of asthma exacerbations than those not taking these drugs
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