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State and federal advertising regulations are strict

These drugs mainly focus on weight loss

Some medical protocols combine them to address both systemic recovery and localized repair

The drugs also seem to reduce inflammation, which may help to reduce risk of cancer

As of early 2026, the FDA proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B bulks list after stating it did not identify a clinical need for outsourcing facilities to compound those drugs from bulk substances

Insurance is rarely an option, either, as no plans cover Retatrutide as of March 2026, since it is awaiting FDA clearance