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Peer Review The peer review history for this article is available at Acknowledgements The authors wish to thank Charlotte Singh, MD, CMPP (Sanofi), for coordinating the development, facilitating author discussions, and providing a critical review of this manuscript

Gastrointestinal side effectsnausea, vomiting, constipation, diarrheaoccur in 2550% of users depending on dose and individual factors
Kayaniyil S, Lozano-Ortega G, Bennett HA, Johnsson K, Shaunik A, Grandy S, et al

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