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Several large, randomized trials have compared cardiovascular outcomes in people treated with OW GLP-1 RAs vs placebo

[DOI] [PubMed] [Google Scholar] Wettergren A, Petersen H, Orskov C, Christiansen J, Sheikh SP, Holst JJ

The primary endpoint was major adverse cardiovascular events (MACE), defined as cardiovascular death, nonfatal heart attack, or nonfatal stroke

"The reason GLP-1 agonist medications are successful in treating diabetes and weight loss is because they promote delayed gastric emptying, early satiety and decreased appetite

Treat this as a map of the conversation then cross-check any specific compound against its actual research and approval status before drawing conclusions

They help you get the nutrients you need without adding too many extra calories