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A recent open label trial compared the efficacy of drugs currently used to lower ICP in IIH (amiloride, furosemide, spironolactone and topiramate) and found a marginal reduction in ICP with no difference between drugs [11]

GLP-1R activation, however, has no significant impact on insulin-like growth factor 1 (IGF-1), IGF binding protein 1 (IGFBP1), or insulin levels in fetal circulation

doi: 10.1155/2013/315848

And the lack of transparent dosing information (proprietary blends obscure exact amounts) makes it impossible to verify whether the product contains research-validated doses of its active ingredients