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Description
Incretin mimetics as a novel therapeutic option for hepatic steatosis

Common side effects can include nausea, vomiting, and gastrointestinal discomfort, which often subside over time

These neurons are activated through GLP-1R signaling, which involves increased cAMP levels and PKA activation that modify the excitability of CCK neurons, potentially leading to altered vagal nerve outflow to the gallbladder

[DOI] [PubMed] [Google Scholar] 97.Eren-Yazicioglu C.Y., Yigit A., Dogruoz R.E., Yapici-Eser H

Cell Commun Signal (2013) 11:34

Before using semaglutide, tell your doctor if you have: personal or family history of medullary thyroid carcinoma (MTC) MEN 2 (multiple endocrine neoplasia syndrome type 2) pancreatitis gallbladder disease kidney disease stomach/intestinal disorders (such as gastroparesis) diabetic eye disease history of suicidal thoughts if pregnant, planning to become pregnant, or breastfeeding Limit alcohol use while taking this medication