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( 10.1056/NEJMoa2028395) [DOI] [PubMed] [Google Scholar] 53.Carbone LJ, Angus PW, Yeomans ND

The SURMOUNT-1 trial data for tirzepatide showed a systolic blood pressure reduction of 6.2 mmHg and diastolic of 4.0 mmHg

Empagliflozin had no clinically relevant effect on the pharmacokinetics of metformin, glimepiride, pioglitazone, sitagliptin, linagliptin, warfarin, digoxin, ramipril, simvastatin, hydrochlorothiazide, torsemide, and oral contraceptives when coadministered in healthy volunteers (see Figure 2)

A novel dual agonist of glucagon-like peptide-1 receptors and neuropeptide Y2 receptors attenuates fentanyl taking and seeking in male rats

Neither group included patients taking concomitant SU therapy

N Engl J Med 381(9):841851