contraindications to glp-1 glp 1 Dr Medica || Clinical MCQ 💉 ❓Most important contraindication of agonists? A. Asthma B. Medullary thyroid carcinoma C. Hypertension D. Diabetes type 2 ⚠️ Educational content only — not medical advice. # Your guide to GLP-1 side

doi:10.1016/j.cell.2016.05.023 (5) Yang D, et al

Notably, while GLP-1 can potentially affect glucagon secretion via its stimulatory effect on the -cells in normal physiological conditions, GLP-1 also inhibits glucagon release in type 1 diabetes, thus demonstrating that GLP-1 inhibition of glucagon secretion does not fully depend on the -cell secretome [516]

But what could be dismissed as first world problems points to something bigger: Medical revolutions require accompanying revolutions across the health care system and that is not happening with GLP-1s

doi: 10.1001/jama.2008.824

Diet induced thermogenesis measured over 24h in a respiration chamber: effect of diet composition

For injectable GLP-1 medications currently in use , patients should be aware of common side effects including nausea, vomiting, diarrhea, and decreased appetite, particularly during dose escalation