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Across all six studies, the safety findings were consistent: no serious adverse events, no immunogenic responses, no changes in IGF-1, no glucose or insulin disruption

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For some, they feel like a breakthrough after years of struggling with blood sugar issues, metabolic dysfunction, or weight gain despite dieting and other approaches

Dose optimization typically takes 812 weeks, with most patients reaching target doses by month 3 of treatment

What Factors Affect These Results

Other clinically relevant GI complications include cholelithiasis, which occurred about 50 % more often, and gastroesophageal reflux disease (GERD), which occurred roughly twice as often, in patients receiving GLP-1 therapies compared with placebo [33]