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The two are listed as side effects of the medication

Conclusion GLP-1 RAs held therapeutic potential for KOA patients with obesity or diabetes, but current evidence remained insufficient, warranting further high-quality RCTs and mechanistic studies to confirm their efficacy and safety

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The relationship appears to be with the rate and magnitude of weight loss itself rather than a direct drug effect

doi:10.1097/GCO.0000000000001015 Graczyk NA, Bisschops J
