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Description
Semaglutide helps control appetite and blood sugar, while orlistat reduces fat absorption
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[1] When combined, the cumulative effect on heart rate and blood pressure may be clinically significant, particularly in patients with pre-existing cardiovascular disease, uncontrolled hypertension, or arrhythmias
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Link to the FDA's statement in comments
A 'bad taste in the mouth' in general can impact appetite and the pleasure of eating
