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A 2023 observational analysis published in the Annals of the Rheumatic Diseases found that patients with inflammatory arthritis who used GLP-1 receptor agonists had lower rates of cardiovascular events, which is notable because cardiovascular disease is a leading cause of death in RA patients

Exclusion criteria observed in Phase 2 trials included individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, given the class-level concern with GLP-1 receptor agonists and C-cell tumours in rodent models [8]

JAMA Internal medicine, 184 (11), 13141323

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