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In contrast with other GLP-1 agonists, maternal exposure to exendin-4 resulted in an increase in pre-weaning fetal growth in one study (56, 57) and lactation (58, 59)

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Emphasizing the value of these incretin-based options for better understanding treatment mechanisms, she said she hopes additional options will emerge to offer benefits beyond weight loss and diabetes management, including disease-modifying effects

Early evidence suggests GLP-1 receptor agonists could influence inflammation pathways that contribute to joint degeneration

GLP-1 medications may also complicate various health conditions

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