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For some Family B members, the binding of the peptide to the TM core may stabilize the formation of an -helix at the N-terminus, which can then activate the receptor 33
In some circumstances, a conditional marketing authorisation may be granted where the benefitrisk balance is positive but further confirmatory data are still awaited
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10.1161/CIRCULATIONAHA.107.739938 193
209 However, cessation rates are low in several countries in Asia (e.g., China, India, Indonesia), Russia, and Central Europe
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