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2020 Jun;28(6):1050-61

Heres what the research says: THE MORE YOU NEED IT, THE LESS YOU MAKE IT Studies show that people carrying extra weight may produce up to 20% less GLP-1 after eating compared to people at a healthy weight

Stenotic vessels likely predispose to and lower the threshold for developing increased ICP, especially in these circumstances (ie, cerebral venous stenosis, cerebral venous sinus thrombosis)

The most common side effects are mild digestive symptoms such as nausea, constipation, diarrhea, or stomach discomfort
Individuals with diabetes are at particularly high risk of NAFLD, theorized to be due to excess energy driving insulin resistance seen in diabetes resulting in increased uptake of free fatty acids in the liver
