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The statistical analyses performed included the Students t -test, one-way analysis of variance (ANOVA) and the MannWhitney test

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In the primary analysis, we identified self-harm by using hospital admission events, thus restricting it to the most serious events to maximise the specificity of the outcome definition, but leading to the possibility of outcome misclassification

Major challenges in TDDS include limited drug-loading capacity and inadequate skin penetration, due to the low mechanical strength of polymeric microneedles or variations in skin properties between individuals

Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimers disease brains