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These hormones are released by the gut in response to food intake and play crucial roles in glucose regulation

The Lack of Clinical Data Currently, there are no large-scale, peer-reviewed clinical trials specifically investigating the combination of a GLP-1 medication like Ozempic or Wegovy with orlistat (often sold as Xenical or the over-the-counter version, Alli)

doi: 10.1016/S2213-8587(20)30075-9 [DOI] [PubMed] [Google Scholar] 47

RELATED: Victoza weight loss Liraglutide side effects As with the name-brand version of the product, the potential side effects of this generic version of liraglutide include: Nausea Diarrhea Vomiting Decreased appetite Indigestion (dyspepsia) Constipation It can cause potentially serious complications, which may include Pancreatitis (inflammation of the pancreas) Kidney impairment or kidney failure Hypoglycemia when used in conjunction with certain other medications, including insulin Acute gallbladder disease The FDA also cautions that people with a personal or family history of medullary thyroid cancer (MTC) or people with multiple endocrine neoplasia syndrome Type 2 (MEN 2) should not take medications containing liraglutide

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"In this study, we've demonstrated in vivo that serotonin administration in mice was able to induce hypoglycaemia by increasing the endogenous secretion of insulin and GLP-1." Thus, the results suggest that the post-meal increase in serotonin observed in individuals with post-bariatric hypoglycaemia may contribute to the increase in insulin secretion and, consequently, the development of hypoglycaemia and symptoms such as dizziness, tremors and mental confusion