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Suppresses glucagon secretion (reduces hepatic glucose production) 3

Backed by the landmark STEP and SUSTAIN clinical trial programmes, it has been studied for weight management, blood sugar control, appetite regulation, and cardiovascular health

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The net benefit of GLP-1 receptor agonists in adults with overweight or obesity who do not have diabetes depends on their weight loss target and willingness to accept harms, according to researchers.Although GLP-1 receptor agonists have demonstrated effectiveness in reducing weight loss and risks for other chronic diseases, questions remain over whether the benefits outweigh the harms of the

Key pathways, including Wnt/-catenin, bone morphogenetic protein 2/Smad, phosphoinositide 3-kinase/Akt and protein kinase A, play a role in this