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Vasodilatory actions of Glucagon-Like peptide 1 are preserved in skeletal and cardiac muscle microvasculature but not in conduit artery in obese humans with vascular insulin resistance

( F ) Top: Representative fluorescence images of GFP:LGG-1 puncta in the posterior bulb of the pharynx of N2 (WT) and myt-1(pan8) I worms

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Cardiovascular risk: beyond diabetes control, semaglutide 2.4 mg reduced major adverse cardiovascular events in adults with overweight/obesity and established cardiovascular disease (CVD)

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Additionally, it prompts the pancreas to release insulin when blood sugar is high, which is why it was originally developed for type 2 diabetes