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Additionally, adaptive thermogenesisa compensatory reduction in energy expenditure beyond what would be predicted by weight loss alonecan further slow metabolic rate, often by approximately 100-300 kcal/day, making continued weight reduction progressively more difficult

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At maximum doses, semaglutide produces approximately 15-17% body weight reduction

Many pharmacies nationwide offer temporary medication storage for traveling patients at no charge

Clinical trial data supporting safety and efficacy