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The solution should be clear and colorlessany cloudiness, discoloration, particles, or crystallization indicates heat damage or contamination

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Overweight and obesity, National Heart, Lung, and Blood Institute (2022) Phentermine Hydrochloride prescribing information, FDA.gov Pharmacologic therapy for obesity, StatPearls (2024) Topiramate and phentermine, StatPearls (2023) Effects on weight reduction and safety of short-term phentermine administration in Korean obese people, Yonsei Medical Journal (2006) Clinical trial for evaluating the efficacy and safety of phentermine hydrochloride in obese patients, The Korean Journal of Obesity (2005) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

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Data were pooled using random-effects models with subgroup analyses by drug type and treatment duration (3, 6, and 12 months)