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JAMA, 315, 5, 510-511

This snapshot provides a side-by-side summary of the most important performance metrics

Why real-world escalation often takes longer In clinical trials, escalation timelines are fixed

41 As discussed above, mitochondrial dysfunction (mitochondrial bioenergetics, calcium buffering) and mitochondrial quality control systems (mitochondrial dynamics, mitophagy, mitochondrial biogenesis) may be involved in the pathological mechanisms of diabetes-related NDs

Individual Drug Methodologies Ozempic, Rybelsus and Wegovy (semaglutide) Keyword search ((+SEMAGLUTID+ OR OZEMPIC OR RYBELSUS OR WEGOVY OR (910463__68__2) OR (910463 2W 68 2W 2) OR NN9535 OR NN__9535 OR (NN 2W 9535) OR NNC 0113-0217 OR (NNC__0113__0217) OR (NNC 2W 0113 2W 0217) OR GTPL9724 OR GTPL__9724 OR (GTPL 2W 9724) OR A10BJ06 OR +EGTFTSD- VSSYLEGQAA+ OR (AIB__8__ARG__34__GLP__1) OR (AIB 2W 8 3W ARG 2W 34 3W GLP 2W 1) OR ((AIB 2W 8 3W ARG 2W 34) 5D (GLP 2W 1)))/TI/AB/CLMS/DESC/ODES/OBJ/ADB/ICLM/KEYW/TX/DESX AND ((NOVO 5D NORDISK)/PA/OPA/NPAN/PAH/PAHN/REAS/REAN OR (NOR- DISK+)/PA/OPA/NPAN/PAH/PAHN/REAS/REAN) Broad drug category Keyword search ((GLUCAGON__LIKE__PEPTIDE__1) OR (GLUCAGON 3W LIKE 3W PEPTIDE 3W 1) OR (GLUCAGON 3W LIKE 3W PEPTIDE) OR (GLP__1) OR (GLP 3W 1) OR GLP__1RA OR (GLP 2W 1RA) OR GLP__1R+ OR GLP1 OR (INCRETIN