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Additional technique considerations: The Association of Diabetes Care & Education Specialists (ADCES) generally recommends 4-mm pen needles for most patients regardless of body size, as they provide sufficient length for subcutaneous delivery while minimizing the risk of intramuscular injection

Nutrient absorption and probiotic support Prolonged reduced food intake on semaglutide can lead to deficiencies in key nutrients that the gut microbiome needs to function optimally

Patients should maintain adequate hydration (68 drinks daily), consume electrolyte-rich foods, and seek medical attention for persistent vomiting/diarrhoea, palpitations, severe muscle weakness, or confusion

Adjustments may be necessary to find the optimal dosage and approach

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