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Regulatory agencies now mandate rigorous lot-to-lot consistency, requiring detailed physicochemical fingerprints that include particle size, polydispersity, ligand stoichiometry, residual solvent levels, and bioactivity, thus necessitating GMP-grade precision at scale [494496]

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Although the relationship between inflammation and clinically reported pain in PCOS has not yet been characterized as extensively as in conditions like osteoarthritis (Slade et al., 2023), the available data strongly suggest similar inflammatory mechanisms

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[1] [2] Allergic reactions, whilst rare, represent another consideration