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Tirzepatide led to a significantly greater reduction in glucose total AUC (41%) compared to semaglutide (34%) and placebo (1% increase)

To view a copy of this licence, visit About this article Cite this article Borlaug, B.A., Zile, M.R., Kramer, C.M

Patients with mild to moderate renal impairment generally do not require dose adjustment, but closer monitoring may be warranted, particularly for signs of gastrointestinal adverse effects that could lead to dehydration and worsening renal function

Unreconstituted powder is far more temperature-stable than reconstituted solution

These newer medications are approved by the FDA for weight loss (provided eligibility criteria are met)

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