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The new, higher-dosed product, given the brand name Wegovy, was FDA approved in June 2021 to treat obesity or other weight-related medical problems ( Figure 2 )

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A sine wave of medication due to the longer time between doses also can create inconsistent maintenance of weight, and any gain that comes as a result of inconsistent medication can lead to stress and fatigue

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These models may not fully recapitulate the chronic, multifactorial nature of human ocular diseases like DR, which involves decades of metabolic dysregulation and low-grade inflammation [130,131,132,133]
