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This underscores the importance of regular monitoring of kidney function in patients taking semaglutide

In fact, Wegovy is now the first weight-loss medication licensed in the UK to reduce cardiovascular risk, including in people living with conditions like hypertension

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A GLP-1R agonist/GIPR antagonist peptide is theoretically possible but few full-length GIP-like antagonists were reported, 60 therefore it requires an array of attempts, at least an alanine-scan experiment of GIP with measuring of affinity

Kyle Simmons, professor of pharmacology and physiology at the OSU Center for Health Sciences

There is no absolute contraindication to using Mounjaro in patients with Graves' disease, according to the UK Summary of Product Characteristics (SmPC) for tirzepatide