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Preliminary findings suggest that these drugs may have even more unexpected off-label uses, such as helping to reduce alcohol use disorder (AUD) , reduce high blood pressure (hypertension) , and provide defense against heart disease and even dementia

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Lancet 2 , 13001304 (1987)

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These medications work by inhibiting cortisol synthesis at various enzymatic steps

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I see patients on GLP-1s who are either maxed out on the recommended dosage, or theyve plateaued in terms of weight loss, said University of Chicago Medicine bariatric surgeon Vanessa Buie, MD, MBA

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Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy rates

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How this renal protection occurs is still unknown

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