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Scientists are also buzzing with excitement about other potential brain-related effects, including possible impacts on addictive behaviors
The heartburn was affecting sleep and making mealtimes dreaded
Indeed, there is evidence that truncated GLP-1 (9-36amide) has no effect on glucose clearance or insulin secretion in healthy humans [196]
1 In one placebo-controlled trial with semaglutide (Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes [SUSTAIN 6]), 10 there was a significant early increase in diabetic retinopathy in patients allocated active therapy, which has been attributed to the rapidity and magnitude of improved glycaemic control (as has been observed in previous studies involving intensive insulin treatment) rather than being a direct adverse drug effect
2025;39(2):e1534
AstraZeneca highlighted that the figure includes a $600 million sales-related milestone receivable from Merck
