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La administracin matutina puede facilitar el monitoreo de sntomas hipoglucmicos durante las horas de vigilia, especialmente importante durante el ajuste de dosis

Chronic stress and elevated cortisol blunt GLP-1 and insulin responsiveness

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This treatment gap, particularly in people with obesity and insulin resistance, could be at least partially overcome with GLP-1 and GIP/GLP-1 receptor agonists, as this clinical setting calls for weight loss (indirect anti-inflammatory action) and a potential direct anti-inflammatory action of these medications to reduce asthma exacerbations, possibly through some of the described mechanisms

Staying on the drugs also did not appear to substantially increase the risks for low or high birth weight or major congenital malformations, although estimates for these outcomes were imprecise

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