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Furthermore, administration of GEP44 resulted in no visceral malaise, as determined in experiments with both rats and shrews 16
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However, after this initial rebound, switching to subcutaneous semaglutide would be expected to result in additional reductions in A1C and weight compared with the other GLP-1 receptor agonists (60)

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doi: 10.1056/NEJMoa2032183 [DOI] [PubMed] [Google Scholar] 12

But while the pill is now mainstream enough that the broader conversation has quieted (just wait until the male contraceptive pill clears clinical trials), GLP-1 drugs continue to make news nearly every day