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I did come across a case study of a woman with stubborn painful periods, unreactive to standard treatments that found relief in GLP-1 agonists 6

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A., Banville S., Ng S., Wang L., Rosenberg S., Marlowe C

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Is a 57 bpm Increase Clinically Significant

The adverse-effect profile was generally the same for metformin monotherapy and sitagliptin/metformin
