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Mol Endocrinol 3: 10141021

Think of GLP-1 probiotics as potentially influencing the gut environmentnot the hormonal pathways that GLP-1 medications work on to drive significant changes in appetite or weight. Taken together, this means GLP-1 probiotics are best approached with realistic expectations

Another observational study from 2024, titled Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide, noted an association between semaglutide, the main drug in Ozempic, and Non - Arteritic Ischemic Optic Neuropathy (NAION), an ocular disease which can cause permanent and severe vision loss

Here we show that oral administration of the non-calorie sweetener, rare sugar d-allulose (d-psicose), induces GLP-1 release, activates vagal afferent signaling, reduces food intake and promotes glucose tolerance in healthy and obese-diabetic animal models

Currently, the US Food and Drug Administration (FDA) has only approved three oral GLP-1s: Rybelsus , which contains the same active ingredient as injectable Wegovy and Ozempic ( semaglutide )