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Waist circumference is a reliable indicator of abdominal obesity, and it is considered a risk factor for ASCVD independent of body mass index [91]

Tirzepatide is a newer dual GLP-1/GIP agonist that targets two receptors simultaneously, and clinical data has demonstrated even greater average weight loss compared to single-receptor medications

Retatrutide discontinuation data remains limited due to its Phase 3 status

But while the numbers on the scale drop, you might notice an unexpected side effect when you look in the mirror: hollow cheeks, sunken eyes, and sagging skin

Medical support: Your doctor is familiar with these medications and can manage side effects and dose adjustments Quality assurance: FDA-approved drugs are manufactured under strict standards

Improved markers like A1C, fasting glucose, and certain cardiovascular risk factors