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Melanie Davies, CBE, MBChB, MD, FRCP, FRCGP, FMedSci, and Vanita R

Although the study was observational, the researchers propose future clinical trials to investigate the link further.

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Conclusion In this NMA, tirzepatide 10 and 15 mg were associated with improved efficacy versus liraglutide, improved or comparable efficacy versus semaglutide, and all interventions had a generally comparable safety profile for achieving weight reduction and reducing cardiometabolic risk factors among patients with obesity or overweight.

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