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Dual GIP/GLP-1 agonists like tirzepatide 15 mg achieve approximately 22.5% average weight loss over 72 weeks

Certain GLP-1s can worsen existing retinopathy in people with diabetes

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Side effect profiles are remarkably similar, with both medications showing nausea rates under 30% and comparable tolerability

Understanding GLP-1 Medications and ADHD Drug Interactions GLP-1 receptor agonists (semaglutide and tirzepatide) work by slowing gastric emptying and signaling fullness in the brain, mechanisms distinct from how ADHD medications function

Relying solely on the medication often results in slower progress, more pronounced plateaus, and a harder time maintaining results once treatment ends