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The main differences across comparison categories are: Mechanism of Action: advantage goes to neither (tie)

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Whilst the effects of GLP-1 RA administration alone on lipogenesis have not been studied, co-administration of GLP-1 RA with glucagon reduces lipogenesis by lowering expression of -hydroxy -methylglutaryl-CoA (HMG-CoA) reductase and sterol regulatory element-binding protein-1c (SBREBP-1C) [127]

Lavu MS, Porto JR, Hecht CJ, et al