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In the present study, enhancement of GlycoPER and OCR demonstrated that TGF-1 + IL-1-stimulated glycolysis provided pyruvate not only for the generation of lactate in the cytosol, but also for the augmentation of mitochondrial oxidative phosphorylation

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Designing these endpoints well from the beginning choosing the right modalities, building the right read methodology, aligning with regulatory expectations before the protocol is locked, is what separates a successful program from an expensive detour

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