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Assis, MD Primary sclerosing cholangitis remains a challenging disease to diagnose and manage, due to varying presentations, associated disease processes, and lack of targeted treatment

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Retatrutide is not licensed by the MHRA and is not available on NHS prescription in the UK

However, semaglutide is not advised for those with a family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, as well as those with pancreatitis or severe gastrointestinal issues
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The subjects in this study were either overweight, obese or had type 2 diabetes
