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2022A comparative transcriptomic analysis of glucagon-like peptide-1 receptor- and glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus

Despite the companys claim that their product promotes appetite control, metabolism support, weight management, and GLP-1 production, there is no reliable scientific evidence demonstrating that these claims are true

If you want a deeper overview of how that hormone affects appetite and digestion, our guide to what GLP-1 does in the body is a helpful next read

In multiple paradigms, animals given GLP-1 agonists reduced their substance intake by 40-60%, even when the substances were freely available

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People in the studies were overweight (BMI 27-29.9 kg/m2) or obese (BMI greater than or equal to 30 kg/m2) before taking Saxenda