glp 1 side effects gastroparesis GI Adverse of Glucagon-Like Peptide-1 Receptor Agonists New data links GLP-1 agonists

[DOI] [PMC free article] [PubMed] [Google Scholar] 187.Jerlhag E

The muscle loss conversation around GLP-1sand now triple agonists like retatrutideneeds more clinical context

Alternative GLP-1 formulations, dose adjustments, or different therapeutic approaches may be more suitable for your individual circumstances

Gastrointestinal Issues Nausea Vomiting Constipation Abdominal discomfort Up to 50% of patients experience GI distress, especially at the start

[DOI] [PubMed] [Google Scholar] Denton E

While GLP-1 RA drugs are effective, their high cost ( US$1,350/month) and side effects (nausea, stomach pain, heartburn) raise concerns, especially about what happens after stopping treatment