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Galectin-3 is another biomarker secreted by activated macrophages and other cells in response to myocardial stress, promoting fibroblast proliferation, collagen deposition, and tissue remodeling, which are central to the pathogenesis of heart failure and atherosclerosis [49]

Metformin is a primary metabolic regulator
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Both regulate blood sugar by lowering blood glucose and improving insulin response

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model 5: PRR 1.57, 95% CI 0.396.42, p = 0.52), breast cancer (12 cases
