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Never change your tirzepatide dose on your own
The relationship between tirzepatide and hormonal cycles is covered in our guide on whether tirzepatide affects your period
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[3] Tirzepatide has a half-life of approximately 5 days, meaning the medication is substantially eliminated from the body within 23 weeks after the last dose
At 15 mg weekly, the maximum dose produces the highest side effect rates but also the best average weight loss results (22.5%)
This consistency advantage is subtle but meaningful over months of weekly injections
