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[DOI] [PubMed] [Google Scholar] 159.Cahill K.N., Amin T., Boutaud O., Printz R., Newcomb D.C., Foer D., Hodson D.J., Broichhagen J., Beckman J.A., Yu C., et al

10.1016/S0140-6736(06)69705-5 8

Published evidence comparing drug costs to outcome measures for health insurers/systems remains sparse, but one study compared the treatment of type 2 diabetes with insulin versus treatment with GLP-1s and found that the higher drug and outpatient costs associated with GLP-1 treatment were offset by a reduction in healthcare costs from emergency visits and inpatient admissions

The earliest form of a GLP-1RA was exenatide, which was a synthetic derivation of the peptide exendin-4, which was found in the saliva of the venomous lizard, the Gila monster [50]

If you have PCOS: Metformin is often continued throughout pregnancy for PCOS patients

Key Insight: GLP-1 Side Effects Are Microbiome-Driven Most people assume that GLP-1 side effects are purely mechanical: the drug slows digestion, so they feel bloated